Pharmacology - PCOL

PCOL 430 Principles of Toxicology 2 hours. Examines the toxic effects of drugs and chemicals on organ systems. Lectures emphasize basic principles, effects on specific organ systems, major classes of toxic chemicals, and specialized topics such as forensic and industrial toxicology.   Same as BPS 430.  Credit is not given for PCOL 430 if the student has credit for EOHS 457.
PCOL 501 Medical Pharmacology I 3 hours. A lecture, conference and laboratory course on human pharmacology.  Drug mechanisms,  toxicities and kinetics are presented as a foundation to therapeutic application.   This is a College of Medicine course that does not follow the regular academic calendar.  Credit is not given for PCOL 501 if the student has credit for PCOL 425.  Prerequisite(s):  Grade of C or better in GCLS 501 and grade of C or better in GCLS 503; or consent of the instructor.
PCOL 502 Medical Pharmacology II 3 hours. Continues PCOL 501. A lecture, conference and laboratory course on human pharmacology.  Drug mechanisms,  toxicities and kinetics are presented as a foundation to therapeutic application.  Credit is not given for PCOL 502 if the student has credit for PCOL 425. College of Medicine course that does not follow the regular academic calendar. Prerequisite(s):  Grade of C or better in GCLS 501 and grade of C or better in GCLS 503; or consent of the instructor.
PCOL 510 Molecular Pharmacology of Platelets, Thrombosis and Vascular System 2 hours. Molecular mechanism and therapeutic approaches to: platelet functions, thrombosis, hemostasis, and vascular biology. The platelet as a model cell for molecular mechanisms of intracellular signal transduction and cell adhesion.  Prerequisite(s): Credit or concurrent registration in GCLS 501 and GCLS 503; or consent of the instructor.
PCOL 530 Pharmacology and Biology of the Vessel Wall 2 hours. Regulation of physiological and pathological processes in the cardiovascular system; e.g. endothelial barrier, cell adhesion, smooth muscle proliferation, angiogenesis, endothelial gene expression. Pharmacological treatment of cardiovascular diseases. Prerequisite(s): Credit or concurrent registration in GCLS 501 and GCLS 503; and consent of the instructor.
PCOL 540 Ion Channels:  Structure, Function, Pharmacology and Pathology 2 hours. The concept of ion channels is treated from the perspectives of their molecular structures and functions. Modulation, pathological conditions (channelopathies), and pharmacological intervention will also be treated.   Same as PHYB 540.  Recommended background:  One undergraduate course in Biochemistry and one in Physiology, or consent of the instructor.
PCOL 550 The Biology and Pharmacology of the Lung 2 hours. Covers topics in lung biology and physiology.  The importance of impaired lung function in inducing lung diseases and potential therapeutics will be discussed. Prerequisite(s): Credit or concurrent registration in GCLS 501; and Credit or concurrent registration in GCLS 503; or consent of the instructor.
PCOL 594 Special Topics 1 hours. Organized presentation and discussion of rapidly developing research areas in molecular, cellular and systems pharmacology. May be repeated. Prerequisite(s): Consent of the instructor. 
PCOL 595 Pharmacology Seminar 1 hours. Presentation of research and/or current literature by invited lecturers and students. Satisfactory/Unsatisfactory grading only. May be repeated.  
PCOL 598 MS Thesis Research 0 TO 16 hours. Thesis work under the supervision of a graduate advisor. Satisfactory/Unsatisfactory grading only.  
PCOL 599 PhD Thesis Research 0 TO 16 hours. Thesis work under the supervision of a graduate advisor. Satisfactory/Unsatisfactory grading only.